Your genetic variation may have a thing to do with your love or hate for coffee.

According to scientists, the jitters you get, the sleepless nights, and the bitter taste might result from how your genes are structured. As part of many people’s routines, a warm coffee cup is necessary to start the day.

In the evenings, when we’re too tired to have a healthy meal, we tend to find ourselves pouring yet another cup of coffee. Little do we know that it messes up our sleep pattern.

Other people loathe coffee, and no matter how sleep-deprived they may be, coffee is never the solution.

A drop of coffee in their mouth may give them jitters, and they may end up staying awake the whole night. Why is this even possible?

For the coffee-lovers, they wouldn’t understand how and why anyone would loathe coffee. I mean, it’s like hating chocolate. Well, the answer lies in the genes.

Science speaks up

Dr. Marilyn Cornelis specializes in caffeine research at Northwestern University in Chicago, Illinois. She states we all have genetic factors that help our bodies self-regulate our caffeine intake.

People who take coffee regularly will develop some level of tolerance to caffeine as time goes by. Still, if you are one of those that avoid coffee because it makes you anxious, sleepless, or nauseous, then it could be a result of variations in your genetic code.

Is it possible to regulate the reactions?

It all boils down to how your body reacts with the caffeine that is already in your system. When it comes to caffeine, there are 2 genes responsible, CYP1A2, and AHR.

The CYP1A2 helps to metabolize roughly 95% of the coffee you ingest, while the AHR is responsible for controlling how much CYP1A2 your body produces.

These genes work together to regulate how much caffeine can circulate in your blood and for how long.

Dr. Cornelis says that if you have a genetic code that leads to decreased caffeine metabolism, you are probably less likely to take coffee than someone with genes that allow increased caffeine metabolism.

Adjust your attitude

Science reveals a completely different set of genes that have a hand in how caffeine affects your brain’s activity and makes you experience other side effects like anxiety and insomnia.

One of the culprits behind the drowsiness and slow nerve activity is also responsible for blocking the release of other feel-good hormones, including dopamine and adenosine. When you have caffeine in your bloodstream, it takes adenosine receptors in your brain, enabling you to stay awake.

In a nutshell, your genetic make-up could be the reason why you loathe coffee or love it so much.

A recent study by the Monell Center in Philadelphia concluded that only 15% of the bitterness of coffee comes from caffeine. In comparison, the other 85% comes from other palettes of bitter compounds. If you are more bitter-sensitive, you are more likely to perceive the bitterness in coffee.